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KMID : 1037820170060010001
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Journal of Pain and Autonomic Disorders
2017 Volume.6 No. 1 p.1 ~ p.5
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Thermoregulation and Sweating
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Suh Bum-Chun
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Abstract
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Human thermoregulation is the maintenance of a constant core body temperature around 37 ℃ and is essential for homeostasis and survival. Skin thermoreceptor activated by the alteration of environmental temperature influences on preoptic hypothalamus and eventually results in activation of mechanism for either warm defense or cold defense. Skin vasoconstriction or vasodilatation is the first effector response for thermoregulation and there are several other effector responses for it. Sweating is one of the major mechanisms for it and also serves for delicate hand manipulation. Excessive sweating such as idiopathic palm hyperhidrosis can be an obstacle for social life and generalized anhidrosis can evoke life-threatening event due to failure of thermoregulation. This review includes physiology of thermoregulation, sweating and major pathologic conditions of sweating disorders. Further understanding of thermoregulation and sweating will be also helpful to assess various autonomic disorders.
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KEYWORD
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Body temperature regulation, Hyperhidrosis, Hypohidrosis, Autonomic nervous system
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